RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-3ccc40ff6ac19c36GRADE VERY_LOW
valerian constituents — sleep
direction BENEFIT · dose 300 mg/kg; 500 mg; 900 mg · duration 8 weeks
Grade basis — weakest-link ceilings
MODERATEdesign
LOWdirectness
LOWextraction
LOWconfidence
MODERATEmethodology
HIGHconsistency
MODERATEnumeric
7bound studies
Bound studies (4 shown of 7)
STU-072ffe97f517b92dCOHORT · HUMAN · 2020 · RoB INSUFFICIENT_INFORMATION
2 endpoints
STU-28c0e57cd23cd096IN_VITRO · IN_VITRO · 2025 · RoB INSUFFICIENT_INFORMATION
1 endpoints
STU-2c6c6c977bc2a270RCT · HUMAN · 2023 · 8 weeks · RoB SOME_CONCERNS
1 endpoints
STU-3ae078f448504a1bRCT · HUMAN · 1999 · RoB SOME_CONCERNS
1 endpoints
Quantitative observations
observation p = 0.4481 · failed extraction
observation p < 0.01 · validated
observation 500 mg · validated
Opposition screen
SCREEN · 14 candidates considered · 3 bound as opposing
SYNTHESIS SYN-8167ad9f36ccf6 — outcome QUALITATIVE_ONLY · BENEFIT ×7 · not_assessed_quantitatively · 7 members
PROVENANCE → epmc:32257874, epmc:40509231, epmc:37160299 · PKG 6f3337772101a53c…
CLAIM · CLM-8fbb277b8c10ae93GRADE VERY_LOW
valerian — mood
direction UNCERTAIN · dose 400 mg/kg; 600 mg · duration 6 weeks
Grade basis — weakest-link ceilings
MODERATEdesign
LOWdirectness
LOWextraction
LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
4bound studies
Bound studies (4 shown of 4)
STU-1ae07a413132171bANIMAL · ANIMAL · 2021 · RoB INSUFFICIENT_INFORMATION
2 endpoints
STU-1f53e3efd9114b10TRIAL · HUMAN · 2001 · 6 weeks · RoB SOME_CONCERNS
3 endpoints
STU-276b7d9a18bedd54TRIAL · HUMAN · 2001 · 6 weeks · RoB SOME_CONCERNS
2 endpoints
STU-d68993719cc00e5eRCT · HUMAN · 2021 · RoB SOME_CONCERNS
2 endpoints
Quantitative observations
observation 24 · validated
observation 600 mg · validated
observation 400 mg/kg · validated
Opposition screen
SCREEN · 8 candidates considered · 3 bound as opposing
SYNTHESIS SYN-e4fc27d00ef513 — outcome QUALITATIVE_ONLY · BENEFIT ×1 · HARM ×1 · UNCERTAIN ×2 · directional_disagreement · 4 members
PROVENANCE → epmc:35082982, crf:10.1002/hup.299, crf:10.1002/ptr.840 · PKG 6f3337772101a53c…
Bounded preview — representative records only. The full release ships 18 claims and 85 observations.