RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-f85df00e21ae21d6GRADE VERY_LOW
red yeast rice — cholesterol
direction BENEFIT · dose UNSPECIFIED · duration 8 week
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
7bound studies
Bound studies (4 shown of 7)
STU-0af9fed7009ce849RCT · HUMAN · 2023 · RoB SOME_CONCERNS
3 endpoints
STU-48e17cf08f64d044SYSTEMATIC_REVIEW · HUMAN · 2016 · RoB INSUFFICIENT_INFORMATION
2 endpoints
STU-548450baf712fd4aANIMAL · ANIMAL · 2025 · RoB INSUFFICIENT_INFORMATION
6 endpoints
STU-64ebf463d5266a06META_ANALYSIS · HUMAN · 2019 · RoB INSUFFICIENT_INFORMATION
2 endpoints
Quantitative observations
observation reduced total cholesterol by 11.4% · failed extraction
observation 8 week · failed extraction
observation 13 · validated
Opposition screen
SCREEN · 23 candidates considered · 3 bound as opposing
SYNTHESIS SYN-c6c25e90467382 — outcome QUALITATIVE_ONLY · BENEFIT ×7 · not_assessed_quantitatively · 7 members
PROVENANCE → epmc:38283922, epmc:27882320, epmc:40851863 · PKG 3cd3e974a5991986…
CLAIM · CLM-b0c3d356a972a39fGRADE VERY_LOW
red yeast rice constituents — cholesterol
direction BENEFIT · dose 10 mg/kg · duration 6 weeks; 8 weeks
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
MODERATEextraction
LOWconfidence
LOWmethodology
MODERATEconsistency
MODERATEnumeric
6bound studies
Bound studies (4 shown of 6)
STU-6e95a46856302c77RCT · HUMAN · 2023 · 6 weeks · RoB HIGH_RISK
3 endpoints
STU-6ec36da62894d7a3META_ANALYSIS · HUMAN · 2024 · RoB INSUFFICIENT_INFORMATION
1 endpoints
STU-6ff7096f5f0474dcANIMAL · ANIMAL · 2022 · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-cdb8a5d16254bf23RCT · HUMAN · 2023 · 8 weeks · RoB SOME_CONCERNS
4 endpoints
Quantitative observations
observation 114 · validated
observation 10 mg/kg · validated
observation 8 weeks · failed extraction
Opposition screen
SCREEN · 23 candidates considered · 3 bound as opposing
SYNTHESIS SYN-48dfbc352c6f1b — outcome QUALITATIVE_ONLY · BENEFIT ×6 · not_assessed_quantitatively · 6 members
PROVENANCE → epmc:36998136, epmc:38794691, epmc:35276836 · PKG 3cd3e974a5991986…
Bounded preview — representative records only. The full release ships 19 claims and 113 observations.