RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-cffe02099d833f4bGRADE VERY_LOW
natto constituents — weight
direction BENEFIT · dose 130 mg/kg; 2.5 g/kg; 300 mg/kg · duration 10 days; 42 days; 8 weeks
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
11bound studies
Bound studies (4 shown of 11)
STU-0d98ab348eb1509cANIMAL · ANIMAL · 2024 · 8 weeks · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-36ebe383ce8e86e5ANIMAL · ANIMAL · 2026 · 42 days · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-3f463444027c0a1dANIMAL · ANIMAL · 2023 · RoB SOME_CONCERNS
3 endpoints
STU-6054774a71db8595ANIMAL · ANIMAL · 2024 · RoB INSUFFICIENT_INFORMATION
3 endpoints
Quantitative observations
duration 8 weeks · failed extraction
p_value p < 0.05 · validated
duration 42 days · failed extraction
Opposition screen
SCREEN · 15 candidates considered · 0 bound as opposing
SYNTHESIS SYN-28fa78e7b67358 — outcome QUALITATIVE_ONLY · BENEFIT ×11 · not_assessed_quantitatively · 11 members
PROVENANCE → epmc:38192042, epmc:IND609404308, epmc:37393326 · PKG 59bfcedefcdb6e02…
CLAIM · CLM-d72870ac11e46ef4GRADE VERY_LOW
natto constituents — microbiome
direction BENEFIT · dose 2.5 g/kg; 300 mg/kg · duration 42 days; 7 days; 8 weeks
Grade basis — weakest-link ceilings
VERY_LOWdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
HIGHconsistency
MODERATEnumeric
8bound studies
Bound studies (4 shown of 8)
STU-0a5d0f2e460b4856ANIMAL · ANIMAL · 2026 · 7 days · RoB INSUFFICIENT_INFORMATION
2 endpoints
STU-0d98ab348eb1509cANIMAL · ANIMAL · 2024 · 8 weeks · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-36ebe383ce8e86e5ANIMAL · ANIMAL · 2026 · 42 days · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-3f463444027c0a1dANIMAL · ANIMAL · 2023 · RoB SOME_CONCERNS
3 endpoints
Quantitative observations
duration 7 days · failed extraction
duration 8 weeks · failed extraction
p_value p < 0.05 · validated
Opposition screen
SCREEN · 15 candidates considered · 0 bound as opposing
SYNTHESIS SYN-25f5bca0324227 — outcome QUALITATIVE_ONLY · BENEFIT ×8 · not_assessed_quantitatively · 8 members
PROVENANCE → epmc:41823856, epmc:38192042, epmc:IND609404308 · PKG 59bfcedefcdb6e02…
Bounded preview — representative records only. The full release ships 35 claims and 147 observations.