RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-153aaa97eb6da220GRADE VERY_LOW
kratom — mood
direction HARM · dose UNSPECIFIED · duration UNSPECIFIED
Grade basis — weakest-link ceilings
VERY_LOWdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
HIGHconsistency
MODERATEnumeric
5bound studies
Bound studies (4 shown of 5)
STU-8f436d5d33743f29UNSPECIFIED · HUMAN · 2025 · RoB NOT_ASSESSABLE
2 endpoints
STU-bee858edbe955deaUNSPECIFIED · HUMAN · 2024 · RoB NOT_ASSESSABLE
1 endpoints
STU-c27e2b0d1aa480bdANIMAL · ANIMAL · 2025 · RoB INSUFFICIENT_INFORMATION
1 endpoints
STU-cc7bbaad1e6e2bf9ANIMAL · ANIMAL · 2026 · RoB SOME_CONCERNS
1 endpoints
Quantitative observations
observation 116 · validated
observation decrease minute volume by 50% · failed extraction
Opposition screen
SCREEN · 13 candidates considered · 3 bound as opposing
SYNTHESIS SYN-a1f69a1471a48b — outcome QUALITATIVE_ONLY · HARM ×5 · not_assessed_quantitatively · 5 members
PROVENANCE → epmc:40823326, epmc:39640144, epmc:41106041 · PKG 1b64cf4022aba55d…
CLAIM · CLM-4239ca40f3cbf412GRADE LOW
kratom — blood pressure
direction HARM · dose UNSPECIFIED · duration UNSPECIFIED
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
HIGHconsistency
LOWnumeric
2bound studies
Bound studies (2 shown of 2)
STU-94c0f0ae50309c0fSYSTEMATIC_REVIEW · IN_VITRO · 2021 · RoB INSUFFICIENT_INFORMATION
4 endpoints
STU-df4e4bbd997c1c0dRCT · HUMAN · 2024 · RoB SOME_CONCERNS
4 endpoints
Quantitative observations
Opposition screen
SCREEN · 2 candidates considered · 0 bound as opposing
SYNTHESIS SYN-e49b22dc121a18 — outcome QUALITATIVE_ONLY · HARM ×2 · not_assessed_quantitatively · 2 members
PROVENANCE → epmc:34646135, epmc:39807458 · PKG 1b64cf4022aba55d…
Bounded preview — representative records only. The full release ships 20 claims and 112 observations.