RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-df115ad613727cdeGRADE VERY_LOW
kava — cancer
direction BENEFIT · dose UNSPECIFIED · duration 7 day; 8 weeks
Grade basis — weakest-link ceilings
MODERATEdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
6bound studies
Bound studies (4 shown of 6)
STU-1af9f0539ce37702IN_VITRO · IN_VITRO · 2020 · RoB INSUFFICIENT_INFORMATION
2 endpoints
STU-483f3e8bc0208bccANIMAL · ANIMAL · 2021 · RoB INSUFFICIENT_INFORMATION
2 endpoints
STU-822f7e125088fc56RCT · HUMAN · 2020 · 7 day · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-d7255549d880267eANIMAL · ANIMAL · 2011 · RoB INSUFFICIENT_INFORMATION
3 endpoints
Quantitative observations
observation 7 day · failed extraction
cancer reduced lung tumor multiplicity by 47% · validated
observation 8 weeks · failed extraction
Opposition screen
SCREEN · 12 candidates considered · 3 bound as opposing
SYNTHESIS SYN-6e7ae1d354f6f0 — outcome PARTIAL_SYNTHESIS · BENEFIT ×6 · not_assessed_quantitatively · 6 members
PROVENANCE → epmc:31711251, epmc:34368644, epmc:32102948 · PKG d0f32690db86b869…
CLAIM · CLM-bed2595342f62e20GRADE VERY_LOW
kava constituents — mood
direction BENEFIT · dose 300 mg; 40 mg/kg · duration 21 days
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
VERY_LOWextraction
VERY_LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
5bound studies
Bound studies (4 shown of 5)
STU-5a47603a93a7234aTRIAL · HUMAN · 2004 · RoB SOME_CONCERNS
1 endpoints
STU-70591be7f1fade24RCT · HUMAN · 2003 · RoB SOME_CONCERNS
1 endpoints
STU-b3059e20a33e771eRCT · HUMAN · 2004 · RoB SOME_CONCERNS
2 endpoints
STU-bd93ec1dff505f37ANIMAL · ANIMAL · 2022 · 21 days · RoB INSUFFICIENT_INFORMATION
1 endpoints
Quantitative observations
observation 40 mg/kg · validated
observation 21 days · failed extraction
observation 50 · validated
Opposition screen
SCREEN · 14 candidates considered · 3 bound as opposing
SYNTHESIS SYN-ccdc15f12df4ef — outcome QUALITATIVE_ONLY · BENEFIT ×5 · not_assessed_quantitatively · 5 members
PROVENANCE → crf:10.1002/ptr.1422, oax:https://openalex.org/W2005720665, crf:10.1002/hup.581 · PKG d0f32690db86b869…
Bounded preview — representative records only. The full release ships 21 claims and 68 observations.