RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-4e4e0ba999d4d01fGRADE VERY_LOW
black cohosh constituents — liver
direction HARM · dose 1000 mg/kg · duration 90 days
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
LOWextraction
LOWconfidence
MODERATEmethodology
HIGHconsistency
MODERATEnumeric
5bound studies
Bound studies (4 shown of 5)
STU-063d1688ebbee2d8META_ANALYSIS · HUMAN · 2011 · RoB INSUFFICIENT_INFORMATION
1 endpoints
STU-1142b332f60c28e8ANIMAL · ANIMAL · 2012 · 90 days · RoB INSUFFICIENT_INFORMATION
2 endpoints
STU-8c12c20cceb8f920ANIMAL · ANIMAL · 2022 · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-b5ca87b107be0bacMETA_ANALYSIS · HUMAN · 2011 · RoB INSUFFICIENT_INFORMATION
1 endpoints
Quantitative observations
observation p=0.37 · validated
observation 517 · validated
observation 90 days · failed extraction
Opposition screen
SCREEN · 8 candidates considered · 2 bound as opposing
SYNTHESIS SYN-c03cb37fc1db03 — outcome QUALITATIVE_ONLY · HARM ×5 · not_assessed_quantitatively · 5 members
PROVENANCE → epmc:21228727, epmc:22687605, epmc:36373576 · PKG 1d14cbe8e6359439…
CLAIM · CLM-c700b713bf8d4fd1GRADE LOW
black cohosh constituents — mood
direction BENEFIT · dose UNSPECIFIED · duration UNSPECIFIED
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
3bound studies
Bound studies (3 shown of 3)
STU-320054bc4a19c76cRCT · HUMAN · 2009 · RoB SOME_CONCERNS
1 endpoints
STU-d51117b3324bc1d5ANIMAL · ANIMAL · 2006 · RoB INSUFFICIENT_INFORMATION
1 endpoints
STU-daea5913a221a05fMETA_ANALYSIS · HUMAN · 2023 · RoB INSUFFICIENT_INFORMATION
1 endpoints
Quantitative observations
observation 15 · validated
observation p = 0.294 | p = 0.79 · failed extraction
observation 310 · validated
Opposition screen
SCREEN · 4 candidates considered · 0 bound as opposing
SYNTHESIS SYN-d1a57a2221646a — outcome QUALITATIVE_ONLY · BENEFIT ×3 · not_assessed_quantitatively · 3 members
PROVENANCE → epmc:19745648, epmc:17177511, epmc:37192826 · PKG 1d14cbe8e6359439…
Bounded preview — representative records only. The full release ships 16 claims and 83 observations.