CN · Field Sheet
FIELD SHEET — BITTER ORANGE MFI-BITORA-20261022-FS
Survey index / BITTER ORANGE

Bitter Orange.

Citrus × aurantium
Synephrine citrus; stimulant and cardiovascular-safety evidence.
SEALED MFI-BITORA-20261022-FS · RELEASED 2026-10-22
SHEET FINGERPRINTMFI-BITORA-20261022-FS
90INCLUDED
1,608EXCLUDED
14DUPLICATE
42NON-TRANSFERABLE
0OUT OF CUTOFF
Survey totalsScroll ↓
1,754records surveyed
90studies
18claims graded
41observations
5,591graph nodes

Claim records

2 shown · bounded preview
RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-5da187e55113f3c0GRADE VERY_LOW
bitter orange constituents — cardiovascular
direction BENEFIT · dose UNSPECIFIED · duration 28 days; 6 weeks
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
7bound studies
Bound studies (4 shown of 7)
STU-15fc14027abf2846
ANIMAL · ANIMAL · 2018 · 6 weeks · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-4acb9493a7185286
ANIMAL · ANIMAL · 2017 · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-703dfce5cfd58245
RCT · HUMAN · 2018 · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-9c89ac672be01589
RCT · HUMAN · 2011 · RoB SOME_CONCERNS
4 endpoints
Quantitative observations
observation 6 weeks · failed extraction
observation 28 days · failed extraction
observation 18 · validated
Opposition screen
SCREEN · 11 candidates considered · 1 bound as opposing
SYNTHESIS SYN-9a6fa178b02aff — outcome QUALITATIVE_ONLY · BENEFIT ×7 · not_assessed_quantitatively · 7 members
PROVENANCE → epmc:29652818, epmc:28752649, epmc:29047215 · PKG 467238c388b3d543…
CLAIM · CLM-5f853b2dd1946f22GRADE VERY_LOW
bitter orange constituents — blood pressure
direction BENEFIT · dose UNSPECIFIED · duration 28 days; 6 weeks
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
MODERATEextraction
LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
6bound studies
Bound studies (4 shown of 6)
STU-15fc14027abf2846
ANIMAL · ANIMAL · 2018 · 6 weeks · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-703dfce5cfd58245
RCT · HUMAN · 2018 · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-9c89ac672be01589
RCT · HUMAN · 2011 · RoB SOME_CONCERNS
4 endpoints
STU-d13720d54cb53749
META_ANALYSIS · HUMAN · 2022 · RoB INSUFFICIENT_INFORMATION
3 endpoints
Quantitative observations
observation 6 weeks · failed extraction
observation 28 days · failed extraction
observation 18 · validated
Opposition screen
SCREEN · 12 candidates considered · 3 bound as opposing
SYNTHESIS SYN-71157ab49d27d9 — outcome QUALITATIVE_ONLY · BENEFIT ×6 · not_assessed_quantitatively · 6 members
PROVENANCE → epmc:29652818, epmc:29047215, epmc:21448304 · PKG 467238c388b3d543…
Bounded preview — representative records only. The full release ships 18 claims and 41 observations.