RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA
CLAIM · CLM-6fe90f93d1a701a5GRADE VERY_LOW
bergamot constituents — cholesterol
direction BENEFIT · dose 100 mg/kg; 50 mg/kg · duration 10 weeks; 12 week; 12 weeks; 14 weeks; 20 weeks; 4 weeks; 8 week
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
LOWextraction
VERY_LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
16bound studies
Bound studies (4 shown of 16)
STU-03f0ce7d3cf6678cRCT · HUMAN · 2024 · RoB SOME_CONCERNS
3 endpoints
STU-07319f79a9d982b8SYSTEMATIC_REVIEW · HUMAN · 2023 · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-126fec0fb2fe547eRCT · HUMAN · 2025 · RoB SOME_CONCERNS
3 endpoints
STU-1ac50d00951afc54ANIMAL · ANIMAL · 2023 · RoB SOME_CONCERNS
3 endpoints
Quantitative observations
n 90 · validated
n 108 · validated
effect reduced by 7.3% · failed extraction
Opposition screen
SCREEN · 38 candidates considered · 0 bound as opposing
SYNTHESIS SYN-443650b3fed7d7 — outcome QUALITATIVE_ONLY · BENEFIT ×16 · not_assessed_quantitatively · 16 members
PROVENANCE → epmc:38892519, epmc:PPR1057200, epmc:37457368 · PKG bffbc68a444c7d4c…
CLAIM · CLM-3b167e6a8bd0f11cGRADE VERY_LOW
bergamot constituents — liver
direction BENEFIT · dose 50 mg/kg · duration 12 weeks; 14 weeks; 16 weeks; 20 weeks; 8 week
Grade basis — weakest-link ceilings
HIGHdesign
LOWdirectness
LOWextraction
VERY_LOWconfidence
MODERATEmethodology
MODERATEconsistency
MODERATEnumeric
15bound studies
Bound studies (4 shown of 15)
STU-03f0ce7d3cf6678cRCT · HUMAN · 2024 · RoB SOME_CONCERNS
3 endpoints
STU-07319f79a9d982b8SYSTEMATIC_REVIEW · HUMAN · 2023 · RoB INSUFFICIENT_INFORMATION
3 endpoints
STU-126fec0fb2fe547eRCT · HUMAN · 2025 · RoB SOME_CONCERNS
3 endpoints
STU-258dc653ff19b7fbANIMAL · ANIMAL · 2024 · 12 weeks · RoB INSUFFICIENT_INFORMATION
3 endpoints
Quantitative observations
n 90 · validated
n 108 · validated
effect reduced by 7.3% · failed extraction
Opposition screen
SCREEN · 22 candidates considered · 0 bound as opposing
SYNTHESIS SYN-211de224d3b046 — outcome QUALITATIVE_ONLY · BENEFIT ×15 · not_assessed_quantitatively · 15 members
PROVENANCE → epmc:38892519, epmc:PPR1057200, epmc:39263833 · PKG bffbc68a444c7d4c…
Bounded preview — representative records only. The full release ships 30 claims and 118 observations.