Claim records

2 shown · bounded preview

RECORD PREVIEW · FIELD RECORD ×2BOUNDED — REAL RELEASED DATA

CLAIM · CLM-35ff2785f3a6f0a9GRADE VERY_LOW

berberine — inflammation

direction BENEFIT · dose 1.24 mg/kg; 100 mg/kg; 200 mg/kg; 30 mg/kg · duration 14 days; 2 months; 7 days

Grade basis — weakest-link ceilings

HIGHdesign

LOWdirectness

LOWextraction

VERY_LOWconfidence

MODERATEmethodology

MODERATEconsistency

MODERATEnumeric

13bound studies

Bound studies (4 shown of 13)

STU-01137ffb4f7c9124

ANIMAL · ANIMAL · 2025 · RoB INSUFFICIENT_INFORMATION

4 endpoints

STU-21eead42ccd5f76e

COHORT · HUMAN · 2024 · 2 months · RoB INSUFFICIENT_INFORMATION

2 endpoints

STU-98036494788b6d9d

ANIMAL · ANIMAL · 2025 · 14 days · RoB INSUFFICIENT_INFORMATION

3 endpoints

STU-9ae1a9be0f547de1

IN_VITRO · IN_VITRO · 2025 · RoB INSUFFICIENT_INFORMATION

5 endpoints

Quantitative observations

observation 7 days · failed extraction

observation 200 mg/kg · validated

observation 1.24 mg/kg · validated

Opposition screen

SCREEN · 16 candidates considered · 3 bound as opposing

SYNTHESIS SYN-9f3940b21d3285 — outcome QUALITATIVE_ONLY · BENEFIT ×13 · not_assessed_quantitatively · 13 members

PROVENANCE → epmc:41164411, epmc:38674895, epmc:41327335 · PKG fa2352b4b1a214fb…

CLAIM · CLM-0af36a7b7e6edeb4GRADE VERY_LOW

berberine — antioxidant

direction BENEFIT · dose 1.24 mg/kg; 100 mg/kg; 200 mg/kg; 30 mg/kg · duration 14 days; 7 days

Grade basis — weakest-link ceilings

LOWdesign

LOWdirectness

MODERATEextraction

LOWconfidence

MODERATEmethodology

MODERATEconsistency

LOWnumeric

8bound studies

Bound studies (4 shown of 8)

STU-040d6f2e06fdf2fe

COHORT · HUMAN · 2026 · RoB SOME_CONCERNS

1 endpoints

STU-32a24e7927c9cb48