{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Yerba Mate",
 "slug": "yerba-mate",
 "dataset_id": "MFI-YERBAM-20261022-FS",
 "engine_version": "2.0-R13",
 "package_sha256_prefix": "7875a52dcb51d7a4",
 "claims": [
  {
   "claim_id": "CLM-5ca505ec613d492d",
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   "outcome": "cardiovascular",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "COHORT",
    "RCT",
    "UNSPECIFIED"
   ],
   "models": [
    "HUMAN"
   ],
   "dose": "3 g",
   "duration": "15 days; 40 days",
   "grade_basis": {
    "bound_studies": 6,
    "confidence_cap": "LOW",
    "consistency_cap": "MODERATE",
    "design_ceiling": "MODERATE",
    "directness_cap": "MODERATE",
    "extraction_cap": "MODERATE",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "downgraded_one_step_for_bound_opposition",
    "quantitative_observations": 11,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "NOT_ASSESSABLE"
   },
   "bound_studies": [
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     "model": "HUMAN",
     "publication_year": 2026,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "blood pressure": "BENEFIT",
      "cardiovascular": "BENEFIT",
      "cholesterol": "UNCERTAIN",
      "glucose": "BENEFIT"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "epmc:42751122"
     ]
    },
    {
     "study_id": "STU-64cf29d5bd96e530",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 2018,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cardiovascular": "BENEFIT"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "epmc:29871836"
     ]
    },
    {
     "study_id": "STU-82b9844145d8b14c",
     "design": "RCT",
     "model": "HUMAN",
     "publication_year": 2018,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "blood pressure": "BENEFIT",
      "cardiovascular": "BENEFIT",
      "skin": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
      "epmc:29681860"
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    },
    {
     "study_id": "STU-87b3e4f443d3168f",
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     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "blood pressure": "BENEFIT",
      "cardiovascular": "BENEFIT",
      "cholesterol": "BENEFIT",
      "glucose": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
      "epmc:29694507"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-2451bfc949796c",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "15 days",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:27223302"
    },
    {
     "observation_id": "QOB-3bbd7bb99ba848",
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     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "40 days",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:19694438"
    },
    {
     "observation_id": "QOB-4e11e28854b2b4",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "3",
     "original_representation": "3 g",
     "original_unit": "g",
     "normalized_value": 3000.0,
     "normalized_unit": "mg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNIT_CONVERSION",
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    },
    {
     "observation_id": "QOB-57e3f553c314ee",
     "observation_kind": "n",
     "effect_measure": "sample size",
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     "original_representation": "15",
     "original_unit": null,
     "normalized_value": 15.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:19694438"
    },
    {
     "observation_id": "QOB-6779ad1beb21ef",
     "observation_kind": "n",
     "effect_measure": "sample size",
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     "original_representation": "23",
     "original_unit": null,
     "normalized_value": 23.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:29681860"
    }
   ],
   "opposition": {
    "considered": 10,
    "bound": 3
   },
   "synthesis": {
    "synthesis_id": "SYN-210405cf4eed11",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 6
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
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     "STU-a4ad34107c2fca1e",
     "STU-d22081355cd73e81"
    ],
    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-422da8bd9ca9f874",
   "object": "yerba mate",
   "outcome": "cholesterol",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "COHORT",
    "RCT",
    "UNSPECIFIED"
   ],
   "models": [
    "HUMAN"
   ],
   "dose": "3 g; 50 g",
   "duration": "12 weeks; 15 days; 40 days",
   "grade_basis": {
    "bound_studies": 5,
    "confidence_cap": "LOW",
    "consistency_cap": "MODERATE",
    "design_ceiling": "MODERATE",
    "directness_cap": "MODERATE",
    "extraction_cap": "MODERATE",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "REJECTED_ONLY",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "downgraded_one_step_for_bound_opposition",
    "quantitative_observations": 14,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "NOT_ASSESSABLE"
   },
   "bound_studies": [
    {
     "study_id": "STU-87b3e4f443d3168f",
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     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "blood pressure": "BENEFIT",
      "cardiovascular": "BENEFIT",
      "cholesterol": "BENEFIT",
      "glucose": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
      "epmc:29694507"
     ]
    },
    {
     "study_id": "STU-a4ad34107c2fca1e",
     "design": "RCT",
     "model": "HUMAN",
     "publication_year": 2009,
     "dose": null,
     "duration": "40 days",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cardiovascular": "BENEFIT",
      "cholesterol": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
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     ]
    },
    {
     "study_id": "STU-d22081355cd73e81",
     "design": "RCT",
     "model": "HUMAN",
     "publication_year": 2016,
     "dose": "3 g",
     "duration": "15 days",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cardiovascular": "BENEFIT",
      "cholesterol": "BENEFIT",
      "inflammation": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
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     ]
    },
    {
     "study_id": "STU-ee6fd3dd80b61d42",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 2015,
     "dose": "50 g",
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cholesterol": "BENEFIT",
      "exercise": "BENEFIT"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
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     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-2451bfc949796c",
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     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
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     "validation_state": "FAILED_VALIDATION",
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    },
    {
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    {
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     "original_representation": "3 g",
     "original_unit": "g",
     "normalized_value": 3000.0,
     "normalized_unit": "mg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
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    {
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     "original_unit": null,
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    {
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   ],
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   },
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    "direction_tally": {
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    },
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    "observations_pooled": 0
   }
  }
 ]
}