{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Wintergreen",
 "slug": "wintergreen",
 "dataset_id": "MFI-WINTE-20261029-FS",
 "engine_version": "2.0-R13",
 "package_sha256_prefix": "1390120b489fdafb",
 "claims": [
  {
   "claim_id": "CLM-3ff0063d0109791f",
   "object": "wintergreen constituents",
   "outcome": "skin",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "RCT"
   ],
   "models": [
    "ANIMAL",
    "HUMAN"
   ],
   "dose": "UNSPECIFIED",
   "duration": "UNSPECIFIED",
   "grade_basis": {
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    "confidence_cap": "VERY_LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "MODERATE",
    "directness_cap": "LOW",
    "extraction_cap": "LOW",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 1,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
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     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cardiovascular": "BENEFIT",
      "skin": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
      "epmc:38706945"
     ]
    },
    {
     "study_id": "STU-bf5ba58919d9848f",
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     "model": "ANIMAL",
     "publication_year": 2017,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "ABSTRACT_ONLY",
     "endpoint_directions": {
      "skin": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "oax:https://openalex.org/W2990881857"
     ]
    },
    {
     "study_id": "STU-d8b3f3bb78b9cc12",
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     "model": "ANIMAL",
     "publication_year": 2017,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "skin": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:29052396"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-5b4023bbc64507",
     "observation_kind": "n",
     "effect_measure": "sample size",
     "original_value": 21,
     "original_representation": "21",
     "original_unit": null,
     "normalized_value": 21.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:38706945"
    }
   ],
   "opposition": {
    "considered": 3,
    "bound": 0
   },
   "synthesis": {
    "synthesis_id": "SYN-363fb88e156a43",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 3
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
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     "STU-bf5ba58919d9848f",
     "STU-d8b3f3bb78b9cc12"
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    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-9e89facfee3a7804",
   "object": "wintergreen constituents",
   "outcome": "cardiovascular",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "RCT"
   ],
   "models": [
    "ANIMAL",
    "HUMAN"
   ],
   "dose": "UNSPECIFIED",
   "duration": "20 days",
   "grade_basis": {
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    "confidence_cap": "VERY_LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "MODERATE",
    "directness_cap": "LOW",
    "extraction_cap": "LOW",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "REJECTED_ONLY",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 3,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
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     "model": "HUMAN",
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     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
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      "skin": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
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     "dose": null,
     "duration": "20 days",
     "extraction_status": "UNASSESSED",
     "full_text_status": "ABSTRACT_ONLY",
     "endpoint_directions": {
      "cardiovascular": "BENEFIT",
      "kidney": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "crf:10.15587/2519-4852.2024.314121"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-5b4023bbc64507",
     "observation_kind": "n",
     "effect_measure": "sample size",
     "original_value": 21,
     "original_representation": "21",
     "original_unit": null,
     "normalized_value": 21.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:38706945"
    },
    {
     "observation_id": "QOB-5f6d57b8e6e82d",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "20 days",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "crf:10.15587/2519-4852.2024.314121"
    },
    {
     "observation_id": "QOB-f7164c25d0a7b8",
     "observation_kind": "effect",
     "effect_measure": null,
     "original_value": null,
     "original_representation": "decreased by 44.87 %",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "crf:10.15587/2519-4852.2024.314121"
    }
   ],
   "opposition": {
    "considered": 2,
    "bound": 0
   },
   "synthesis": {
    "synthesis_id": "SYN-7954129e18817a",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 2
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-13772ada141b81ea",
     "STU-64fd547ec9670d46"
    ],
    "observations_pooled": 0
   }
  }
 ]
}