{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Tremella",
 "slug": "tremella",
 "dataset_id": "MFI-TREMEL-20261022-FS",
 "engine_version": "2.0-R13",
 "package_sha256_prefix": "d6e981d63d2f74d7",
 "claims": [
  {
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   "outcome": "antioxidant",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "models": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "dose": "3.0 g/kg",
   "duration": "14 days",
   "grade_basis": {
    "bound_studies": 3,
    "confidence_cap": "LOW",
    "consistency_cap": "MODERATE",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 3,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
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     "model": "ANIMAL",
     "publication_year": 2019,
     "dose": "3.0 g/kg",
     "duration": "14 days",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "exercise": "BENEFIT",
      "liver": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
      "epmc:31889793"
     ]
    },
    {
     "study_id": "STU-157c94c1e996bb1d",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
     "publication_year": 2024,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cognition": "BENEFIT",
      "gastrointestinal": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:IND608359726"
     ]
    },
    {
     "study_id": "STU-627973d04d92f2ed",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2025,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:41232497"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-5307418246b9cb",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "3.0",
     "original_representation": "3.0 g/kg",
     "original_unit": "g/kg",
     "normalized_value": 3.0,
     "normalized_unit": "g/kg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNNORMALIZED",
     "record_id": "epmc:31889793"
    },
    {
     "observation_id": "QOB-8a38c015a1702a",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "14 days",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:31889793"
    },
    {
     "observation_id": "QOB-c4fc7e58374ab4",
     "observation_kind": "n",
     "effect_measure": "sample size",
     "original_value": 12,
     "original_representation": "12",
     "original_unit": null,
     "normalized_value": 12.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:31889793"
    }
   ],
   "opposition": {
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    "bound": 3
   },
   "synthesis": {
    "synthesis_id": "SYN-a38b8feae9cb64",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 3
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-0dc4d482c2fefc68",
     "STU-157c94c1e996bb1d",
     "STU-627973d04d92f2ed"
    ],
    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-0906c960c0e6528d",
   "object": "tremella constituents",
   "outcome": "glucose",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "models": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "dose": "2 g/kg",
   "duration": "8 weeks",
   "grade_basis": {
    "bound_studies": 2,
    "confidence_cap": "LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "LOW",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 2,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
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     "model": "ANIMAL",
     "publication_year": 2022,
     "dose": "2 g/kg",
     "duration": "8 weeks",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cholesterol": "BENEFIT",
      "glucose": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:35458264"
     ]
    },
    {
     "study_id": "STU-6f8df690ed266410",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
     "publication_year": 2025,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cholesterol": "BENEFIT",
      "cognition": "BENEFIT",
      "glucose": "BENEFIT",
      "liver": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:39319532"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-6b37ce8ebe411b",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "2",
     "original_representation": "2 g/kg",
     "original_unit": "g/kg",
     "normalized_value": 2.0,
     "normalized_unit": "g/kg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNNORMALIZED",
     "record_id": "epmc:35458264"
    },
    {
     "observation_id": "QOB-90a68aea9a317b",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "8 weeks",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:35458264"
    }
   ],
   "opposition": {
    "considered": 6,
    "bound": 3
   },
   "synthesis": {
    "synthesis_id": "SYN-4ad993591d19ef",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
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    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-49c46b4a668bad0c",
     "STU-6f8df690ed266410"
    ],
    "observations_pooled": 0
   }
  }
 ]
}