{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Shiitake",
 "slug": "shiitake",
 "dataset_id": "MFI-SHIITA-20261022-FS",
 "engine_version": "2.0-R13",
 "package_sha256_prefix": "f655c800d3b8d846",
 "claims": [
  {
   "claim_id": "CLM-b60f69865acecb22",
   "object": "shiitake",
   "outcome": "skin",
   "direction": "NULL",
   "grade": "INSUFFICIENT",
   "design": [
    "UNSPECIFIED"
   ],
   "models": [
    "HUMAN"
   ],
   "dose": "UNSPECIFIED",
   "duration": "UNSPECIFIED",
   "grade_basis": {
    "bound_studies": 3,
    "confidence_cap": "LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "INSUFFICIENT",
    "directness_cap": "MODERATE",
    "extraction_cap": "LOW",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 1,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "NOT_ASSESSABLE"
   },
   "bound_studies": [
    {
     "study_id": "STU-2085df822775faf5",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 2026,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "skin": "UNCERTAIN"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "epmc:41827968"
     ]
    },
    {
     "study_id": "STU-724a4ea5b4a88b5b",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 2024,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "skin": "UNCERTAIN"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "epmc:39077726"
     ]
    },
    {
     "study_id": "STU-e0c9f75e554519d4",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 1992,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "ABSTRACT_ONLY",
     "endpoint_directions": {
      "skin": "UNCERTAIN"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "crf:10.1111/j.1600-0536.1992.tb05211.x"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-514e6d31293b3b",
     "observation_kind": "n",
     "effect_measure": "sample size",
     "original_value": 51,
     "original_representation": "51",
     "original_unit": null,
     "normalized_value": 51.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "crf:10.1111/j.1600-0536.1992.tb05211.x"
    }
   ],
   "opposition": {
    "considered": 4,
    "bound": 3
   },
   "synthesis": {
    "synthesis_id": "SYN-aaf1f3b404e07f",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "UNCERTAIN": 3
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-2085df822775faf5",
     "STU-724a4ea5b4a88b5b",
     "STU-e0c9f75e554519d4"
    ],
    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-1e6956344efd107d",
   "object": "shiitake",
   "outcome": "cholesterol",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL"
   ],
   "models": [
    "ANIMAL"
   ],
   "dose": "800 mg/kg",
   "duration": "4 weeks",
   "grade_basis": {
    "bound_studies": 1,
    "confidence_cap": "LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "LOW",
    "numeric_states": [
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 2,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-b29be6691a3cae2e",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2024,
     "dose": "800 mg/kg",
     "duration": "4 weeks",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cholesterol": "BENEFIT",
      "mortality": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:38962708"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-af733caaa21762",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "4 weeks",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:38962708"
    },
    {
     "observation_id": "QOB-df469c9ed5f4a9",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "800",
     "original_representation": "800 mg/kg",
     "original_unit": "mg/kg",
     "normalized_value": 800.0,
     "normalized_unit": "mg/kg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNNORMALIZED",
     "record_id": "epmc:38962708"
    }
   ],
   "opposition": {
    "considered": 2,
    "bound": 0
   },
   "synthesis": {
    "synthesis_id": "SYN-d012675d205471",
    "synthesis_outcome": "SYNTHESIS_INAPPROPRIATE",
    "direction_tally": {
     "BENEFIT": 1
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-b29be6691a3cae2e"
    ],
    "observations_pooled": 0
   }
  }
 ]
}