{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Eggs",
 "slug": "eggs",
 "dataset_id": "MFI-EGGS-20261013-FS",
 "engine_version": "2.1.0",
 "package_sha256_prefix": "bf499ddc8af2fe1e",
 "claims": [
  {
   "claim_id": "CLM-c162de8c9c1b2431",
   "object": "eggs constituents",
   "outcome": "weight",
   "direction": "BENEFIT",
   "grade": "LOW",
   "design": [
    "ANIMAL",
    "RCT",
    "UNSPECIFIED"
   ],
   "models": [
    "ANIMAL",
    "HUMAN"
   ],
   "dose": "80 mg/kg",
   "duration": "12 weeks; 15 weeks; 8 weeks",
   "grade_basis": {
    "design_ceiling": "MODERATE",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "confidence_cap": "LOW",
    "rob_cap": "MODERATE",
    "consistency_cap": "MODERATE",
    "numeric_cap": "MODERATE",
    "bound_studies": 6,
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-1005777777fdaf19",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2025,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "immune": "BENEFIT",
      "microbiome": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:41374020"
     ]
    },
    {
     "study_id": "STU-131eafe66132b784",
     "design": "RCT",
     "model": "HUMAN",
     "publication_year": 2026,
     "dose": null,
     "duration": "8 weeks",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cholesterol": "BENEFIT",
      "glucose": "BENEFIT"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
      "epmc:42261556"
     ]
    },
    {
     "study_id": "STU-55ba8dd26c7f4ae9",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 2026,
     "dose": null,
     "duration": "12 weeks",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cancer": "BENEFIT",
      "kidney": "BENEFIT",
      "liver": "BENEFIT"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "epmc:42005183"
     ]
    },
    {
     "study_id": "STU-78b96ddef9d98d43",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2026,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "immune": "BENEFIT",
      "microbiome": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:IND609221162"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-ccbfdf9f144385",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "8 weeks",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:42261556"
    },
    {
     "observation_id": "QOB-5b51af6b5da400",
     "observation_kind": "n",
     "effect_measure": "sample size",
     "original_value": 33,
     "original_representation": "33",
     "original_unit": null,
     "normalized_value": 33.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:42005183"
    },
    {
     "observation_id": "QOB-8ab2a8d5683801",
     "observation_kind": "p_value",
     "effect_measure": "p-value",
     "original_value": "0.03",
     "original_representation": "p=0.03",
     "original_unit": null,
     "normalized_value": 0.03,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:42005183"
    },
    {
     "observation_id": "QOB-f55a5c5f0f4009",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "12 weeks",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:42005183"
    },
    {
     "observation_id": "QOB-fdedcb672a7e51",
     "observation_kind": "p_value",
     "effect_measure": "p-value",
     "original_value": "0.05",
     "original_representation": "p < 0.05",
     "original_unit": null,
     "normalized_value": 0.05,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:IND609221162"
    }
   ],
   "opposition": {
    "considered": 8,
    "bound": 0
   },
   "synthesis": {
    "synthesis_id": "SYN-604095cf8b13a9",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 6
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-1005777777fdaf19",
     "STU-131eafe66132b784",
     "STU-55ba8dd26c7f4ae9",
     "STU-78b96ddef9d98d43",
     "STU-abfa5168b4a0b943",
     "STU-ecf508790cec65d8"
    ],
    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-b84f8b745018d47e",
   "object": "eggs constituents",
   "outcome": "liver",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "UNSPECIFIED"
   ],
   "models": [
    "ANIMAL",
    "HUMAN"
   ],
   "dose": "500 mg/kg; 80 mg/kg",
   "duration": "12 weeks; 15 weeks; 8 weeks",
   "grade_basis": {
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "confidence_cap": "LOW",
    "rob_cap": "MODERATE",
    "consistency_cap": "HIGH",
    "numeric_cap": "MODERATE",
    "bound_studies": 4,
    "rob_worst_judgment": "NOT_ASSESSABLE"
   },
   "bound_studies": [
    {
     "study_id": "STU-55ba8dd26c7f4ae9",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 2026,
     "dose": null,
     "duration": "12 weeks",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cancer": "BENEFIT",
      "kidney": "BENEFIT",
      "liver": "BENEFIT"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "epmc:42005183"
     ]
    },
    {
     "study_id": "STU-beff8cb0084db816",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2026,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "exercise": "BENEFIT",
      "glucose": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:41252862"
     ]
    },
    {
     "study_id": "STU-d1f1cefd8367ad6b",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2026,
     "dose": "500 mg/kg",
     "duration": "8 weeks",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cholesterol": "BENEFIT",
      "liver": "BENEFIT",
      "microbiome": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:42119181"
     ]
    },
    {
     "study_id": "STU-ecf508790cec65d8",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2025,
     "dose": "80 mg/kg",
     "duration": "15 weeks",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cholesterol": "BENEFIT",
      "liver": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:41225553"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-5b51af6b5da400",
     "observation_kind": "n",
     "effect_measure": "sample size",
     "original_value": 33,
     "original_representation": "33",
     "original_unit": null,
     "normalized_value": 33.0,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:42005183"
    },
    {
     "observation_id": "QOB-8ab2a8d5683801",
     "observation_kind": "p_value",
     "effect_measure": "p-value",
     "original_value": "0.03",
     "original_representation": "p=0.03",
     "original_unit": null,
     "normalized_value": 0.03,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:42005183"
    },
    {
     "observation_id": "QOB-f55a5c5f0f4009",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "12 weeks",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:42005183"
    },
    {
     "observation_id": "QOB-e31178880dde38",
     "observation_kind": "p_value",
     "effect_measure": "p-value",
     "original_value": "0.05",
     "original_representation": "p < 0.05",
     "original_unit": null,
     "normalized_value": 0.05,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:41252862"
    },
    {
     "observation_id": "QOB-442dfe8aeaa1c4",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "500",
     "original_representation": "500 mg/kg",
     "original_unit": "mg/kg",
     "normalized_value": 500.0,
     "normalized_unit": "mg/kg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNNORMALIZED",
     "record_id": "epmc:42119181"
    },
    {
     "observation_id": "QOB-563451b2cc91cd",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "8 weeks",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:42119181"
    }
   ],
   "opposition": {
    "considered": 5,
    "bound": 0
   },
   "synthesis": {
    "synthesis_id": "SYN-cbbfd768a47dbd",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 4
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-55ba8dd26c7f4ae9",
     "STU-beff8cb0084db816",
     "STU-d1f1cefd8367ad6b",
     "STU-ecf508790cec65d8"
    ],
    "observations_pooled": 0
   }
  }
 ]
}