{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Colloidal Silver",
 "slug": "colloidal-silver",
 "dataset_id": "MFI-COLSIL-20261023-FS",
 "engine_version": "2.0-R13",
 "package_sha256_prefix": "3ba2a8bf92cba15d",
 "claims": [
  {
   "claim_id": "CLM-092f068556dae43b",
   "object": "colloidal silver",
   "outcome": "skin",
   "direction": "HARM",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL"
   ],
   "models": [
    "ANIMAL"
   ],
   "dose": "UNSPECIFIED",
   "duration": "UNSPECIFIED",
   "grade_basis": {
    "bound_studies": 1,
    "confidence_cap": "VERY_LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "LOW",
    "numeric_cap": "LOW",
    "numeric_states": [
     "NO_NUMERICS_PRESENT"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 0,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-4e56748a95408725",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2015,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "ABSTRACT_ONLY",
     "endpoint_directions": {
      "skin": "HARM"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "oax:https://openalex.org/W4236060615"
     ]
    }
   ],
   "quantitative_observations": [],
   "opposition": {
    "considered": 2,
    "bound": 1
   },
   "synthesis": {
    "synthesis_id": "SYN-e714e8ab98989f",
    "synthesis_outcome": "SYNTHESIS_INAPPROPRIATE",
    "direction_tally": {
     "HARM": 1
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-4e56748a95408725"
    ],
    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-6b6496d315cbf58c",
   "object": "colloidal silver",
   "outcome": "inflammation",
   "direction": "NULL",
   "grade": "VERY_LOW",
   "design": [
    "IN_VITRO"
   ],
   "models": [
    "IN_VITRO"
   ],
   "dose": "UNSPECIFIED",
   "duration": "UNSPECIFIED",
   "grade_basis": {
    "bound_studies": 1,
    "confidence_cap": "LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "LOW",
    "numeric_states": [
     "NO_NUMERICS_PRESENT"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 0,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-2981adf6f8561fc9",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
     "publication_year": 2017,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "inflammation": "UNCERTAIN",
      "skin": "UNCERTAIN"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:28475520"
     ]
    }
   ],
   "quantitative_observations": [],
   "opposition": {
    "considered": 1,
    "bound": 1
   },
   "synthesis": {
    "synthesis_id": "SYN-b1c401a6ab73a2",
    "synthesis_outcome": "SYNTHESIS_INAPPROPRIATE",
    "direction_tally": {
     "UNCERTAIN": 1
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-2981adf6f8561fc9"
    ],
    "observations_pooled": 0
   }
  }
 ]
}