{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Chaga",
 "slug": "chaga",
 "dataset_id": "MFI-CHAGA-20261019-FS",
 "engine_version": "2.1.0",
 "package_sha256_prefix": "d2d997be318d1dd9",
 "claims": [
  {
   "claim_id": "CLM-402f8438e392bc00",
   "object": "chaga constituents",
   "outcome": "inflammation",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "models": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "dose": "UNSPECIFIED",
   "duration": "UNSPECIFIED",
   "grade_basis": {
    "bound_studies": 4,
    "confidence_cap": "VERY_LOW",
    "consistency_cap": "MODERATE",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "LOW",
    "numeric_cap": "LOW",
    "numeric_states": [
     "NO_NUMERICS_PRESENT"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 0,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-0af04b2f86740bd7",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2024,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cognition": "BENEFIT",
      "glucose": "BENEFIT",
      "inflammation": "BENEFIT",
      "liver": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:PPR938657"
     ]
    },
    {
     "study_id": "STU-9a45040a28dba299",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2025,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cognition": "BENEFIT",
      "inflammation": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:40429872"
     ]
    },
    {
     "study_id": "STU-e51448160162c0c7",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2025,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "cancer": "BENEFIT",
      "immune": "BENEFIT",
      "inflammation": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:40662772"
     ]
    },
    {
     "study_id": "STU-f9d45cf56f670e58",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
     "publication_year": 2004,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "ABSTRACT_ONLY",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "inflammation": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "crf:10.1002/biof.552210120"
     ]
    }
   ],
   "quantitative_observations": [],
   "opposition": {
    "considered": 7,
    "bound": 3
   },
   "synthesis": {
    "synthesis_id": "SYN-8d84cc838eba54",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 4
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-0af04b2f86740bd7",
     "STU-9a45040a28dba299",
     "STU-e51448160162c0c7",
     "STU-f9d45cf56f670e58"
    ],
    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-5e15bdfdfe40401e",
   "object": "chaga constituents",
   "outcome": "antioxidant",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "IN_VITRO",
    "UNSPECIFIED"
   ],
   "models": [
    "ANIMAL",
    "HUMAN",
    "IN_VITRO"
   ],
   "dose": "100 mg/kg",
   "duration": "7 days",
   "grade_basis": {
    "bound_studies": 4,
    "confidence_cap": "VERY_LOW",
    "consistency_cap": "MODERATE",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "LOW",
    "numeric_cap": "LOW",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 2,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-68d4d135ff0826dc",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2011,
     "dose": "100 mg/kg",
     "duration": "7 days",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cognition": "BENEFIT",
      "mood": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:21779570"
     ]
    },
    {
     "study_id": "STU-69df680712faccbc",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2020,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "ABSTRACT_ONLY",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "immune": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "crf:10.1101/2020.06.19.161182"
     ]
    },
    {
     "study_id": "STU-6b2554e51a785bc4",
     "design": "UNSPECIFIED",
     "model": "HUMAN",
     "publication_year": 2024,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT"
     },
     "risk_of_bias": "NOT_ASSESSABLE",
     "provenance_refs": [
      "epmc:39202879"
     ]
    },
    {
     "study_id": "STU-f9d45cf56f670e58",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
     "publication_year": 2004,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "ABSTRACT_ONLY",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "inflammation": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "crf:10.1002/biof.552210120"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-a4d0dfdd39744f",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "7 days",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:21779570"
    },
    {
     "observation_id": "QOB-dcf8c982f565d1",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "100",
     "original_representation": "100 mg/kg",
     "original_unit": "mg/kg",
     "normalized_value": 100.0,
     "normalized_unit": "mg/kg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNNORMALIZED",
     "record_id": "epmc:21779570"
    }
   ],
   "opposition": {
    "considered": 8,
    "bound": 3
   },
   "synthesis": {
    "synthesis_id": "SYN-636b4f54abb84a",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 4
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-68d4d135ff0826dc",
     "STU-69df680712faccbc",
     "STU-6b2554e51a785bc4",
     "STU-f9d45cf56f670e58"
    ],
    "observations_pooled": 0
   }
  }
 ]
}