{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "California Poppy",
 "slug": "california-poppy",
 "dataset_id": "MFI-CALPOP-20261022-FS",
 "engine_version": "2.0-R13",
 "package_sha256_prefix": "c401f0126963efd1",
 "claims": [
  {
   "claim_id": "CLM-cd8635baa144cfe5",
   "object": "california poppy constituents",
   "outcome": "antioxidant",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "models": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "dose": "68 mg/kg",
   "duration": "UNSPECIFIED",
   "grade_basis": {
    "bound_studies": 4,
    "confidence_cap": "LOW",
    "consistency_cap": "MODERATE",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 2,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
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     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cancer": "BENEFIT",
      "inflammation": "BENEFIT",
      "skin": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:41304926"
     ]
    },
    {
     "study_id": "STU-50e983628edb97f9",
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     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cancer": "UNCERTAIN",
      "inflammation": "HARM",
      "kidney": "UNCERTAIN",
      "liver": "UNCERTAIN",
      "mood": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:41431509"
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    },
    {
     "study_id": "STU-74e5763efe6c2b5f",
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     "model": "IN_VITRO",
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     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cancer": "BENEFIT",
      "immune": "BENEFIT",
      "inflammation": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:42315562"
     ]
    },
    {
     "study_id": "STU-9e530bf69c845be4",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2026,
     "dose": "68 mg/kg",
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "liver": "BENEFIT",
      "weight": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:42127849"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-3f82b91be4a227",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "68",
     "original_representation": "68 mg/kg",
     "original_unit": "mg/kg",
     "normalized_value": 68.0,
     "normalized_unit": "mg/kg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNNORMALIZED",
     "record_id": "epmc:42127849"
    }
   ],
   "opposition": {
    "considered": 4,
    "bound": 0
   },
   "synthesis": {
    "synthesis_id": "SYN-170f771a3bb08f",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
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    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
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     "STU-50e983628edb97f9",
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     "STU-9e530bf69c845be4"
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    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-6a0ea2f4b2776ad5",
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   "outcome": "inflammation",
   "direction": "BENEFIT",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "models": [
    "ANIMAL",
    "IN_VITRO"
   ],
   "dose": "UNSPECIFIED",
   "duration": "UNSPECIFIED",
   "grade_basis": {
    "bound_studies": 3,
    "confidence_cap": "LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 3,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
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     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cancer": "BENEFIT",
      "inflammation": "BENEFIT",
      "skin": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
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     ]
    },
    {
     "study_id": "STU-74e5763efe6c2b5f",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
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     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "BENEFIT",
      "cancer": "BENEFIT",
      "immune": "BENEFIT",
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     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
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    {
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     "model": "ANIMAL",
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     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "inflammation": "BENEFIT"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:42644740"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-da03183b4c1423",
     "observation_kind": "effect",
     "effect_measure": null,
     "original_value": null,
     "original_representation": "p < 0.001",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:42644740"
    },
    {
     "observation_id": "QOB-fba223cb301416",
     "observation_kind": "effect",
     "effect_measure": "percent change",
     "original_value": "45.7",
     "original_representation": "reduced il-1β levels by 45.7%",
     "original_unit": null,
     "normalized_value": 45.7,
     "normalized_unit": null,
     "endpoint": "inflammation",
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:41304926"
    },
    {
     "observation_id": "QOB-fc04f3b612c995",
     "observation_kind": "p_value",
     "effect_measure": "p-value",
     "original_value": "0.01",
     "original_representation": "p < 0.01",
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     "normalized_value": 0.01,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:42644740"
    }
   ],
   "opposition": {
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    "bound": 1
   },
   "synthesis": {
    "synthesis_id": "SYN-ca0d08f272c5e4",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "BENEFIT": 3
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
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     "STU-92e69d0d3dc62c15"
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    "observations_pooled": 0
   }
  }
 ]
}