{
 "artifact_type": "BOUNDED_EVIDENCE_PREVIEW",
 "preview_boundary": "Deliberately bounded representative records for demonstration. Not a complete claim, evidence, study, or provenance inventory.",
 "food": "Apricot Kernels",
 "slug": "apricot-kernels",
 "dataset_id": "MFI-APRKER-20261023-FS",
 "engine_version": "2.0-R13",
 "package_sha256_prefix": "4cbba017fd9a39c9",
 "claims": [
  {
   "claim_id": "CLM-234c3846142a4ea6",
   "object": "apricot kernels constituents",
   "outcome": "liver",
   "direction": "HARM",
   "grade": "VERY_LOW",
   "design": [
    "ANIMAL"
   ],
   "models": [
    "ANIMAL"
   ],
   "dose": "6000 mg/kg",
   "duration": "28 days",
   "grade_basis": {
    "bound_studies": 2,
    "confidence_cap": "LOW",
    "consistency_cap": "HIGH",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "LOW",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 2,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-ca81474f2af4153e",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2011,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "liver": "HARM"
     },
     "risk_of_bias": "SOME_CONCERNS",
     "provenance_refs": [
      "epmc:21736706"
     ]
    },
    {
     "study_id": "STU-f796c394c73d825c",
     "design": "ANIMAL",
     "model": "ANIMAL",
     "publication_year": 2025,
     "dose": "6000 mg/kg",
     "duration": "28 days",
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "kidney": "HARM",
      "liver": "HARM",
      "mortality": "HARM",
      "weight": "HARM"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:40007548"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-693f869744b0d7",
     "observation_kind": "duration",
     "effect_measure": "duration",
     "original_value": null,
     "original_representation": "28 days",
     "original_unit": null,
     "normalized_value": null,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "FAILED_EXTRACTION",
     "validation_state": "FAILED_VALIDATION",
     "transformation": "NONE",
     "record_id": "epmc:40007548"
    },
    {
     "observation_id": "QOB-d3369ba278f5ea",
     "observation_kind": "dose",
     "effect_measure": "dose",
     "original_value": "6000",
     "original_representation": "6000 mg/kg",
     "original_unit": "mg/kg",
     "normalized_value": 6000.0,
     "normalized_unit": "mg/kg",
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "UNNORMALIZED",
     "record_id": "epmc:40007548"
    }
   ],
   "opposition": {
    "considered": 3,
    "bound": 1
   },
   "synthesis": {
    "synthesis_id": "SYN-b25b4ed8340758",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "HARM": 2
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-ca81474f2af4153e",
     "STU-f796c394c73d825c"
    ],
    "observations_pooled": 0
   }
  },
  {
   "claim_id": "CLM-3eb3825bde07d034",
   "object": "apricot kernels constituents",
   "outcome": "antioxidant",
   "direction": "NULL",
   "grade": "VERY_LOW",
   "design": [
    "IN_VITRO"
   ],
   "models": [
    "IN_VITRO"
   ],
   "dose": "UNSPECIFIED",
   "duration": "UNSPECIFIED",
   "grade_basis": {
    "bound_studies": 2,
    "confidence_cap": "LOW",
    "consistency_cap": "MODERATE",
    "design_ceiling": "VERY_LOW",
    "directness_cap": "LOW",
    "extraction_cap": "MODERATE",
    "numeric_cap": "MODERATE",
    "numeric_states": [
     "NO_NUMERICS_PRESENT",
     "VALIDATED_EXTRACTION"
    ],
    "opposition_adj": "none",
    "quantitative_observations": 2,
    "rob_cap": "MODERATE",
    "rob_worst_judgment": "INSUFFICIENT_INFORMATION"
   },
   "bound_studies": [
    {
     "study_id": "STU-9b0ebbc98359d4c3",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
     "publication_year": 2026,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "UNCERTAIN",
      "cardiovascular": "UNCERTAIN",
      "inflammation": "UNCERTAIN"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:41863498"
     ]
    },
    {
     "study_id": "STU-ea5b5f1958d96737",
     "design": "IN_VITRO",
     "model": "IN_VITRO",
     "publication_year": 2009,
     "dose": null,
     "duration": null,
     "extraction_status": "UNASSESSED",
     "full_text_status": "FULL_TEXT",
     "endpoint_directions": {
      "antioxidant": "UNCERTAIN"
     },
     "risk_of_bias": "INSUFFICIENT_INFORMATION",
     "provenance_refs": [
      "epmc:19330262"
     ]
    }
   ],
   "quantitative_observations": [
    {
     "observation_id": "QOB-923b2fc4d039f5",
     "observation_kind": "p_value",
     "effect_measure": "p-value",
     "original_value": "0.01",
     "original_representation": "p < 0.01",
     "original_unit": null,
     "normalized_value": 0.01,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "VALIDATED",
     "validation_state": "VALID",
     "transformation": "IDENTITY",
     "record_id": "epmc:41863498"
    },
    {
     "observation_id": "QOB-984e3770253c25",
     "observation_kind": "effect",
     "effect_measure": "percent change",
     "original_value": "16.2",
     "original_representation": "reduction in haec viability, increasing it by 16.2%",
     "original_unit": null,
     "normalized_value": 16.2,
     "normalized_unit": null,
     "endpoint": null,
     "extraction_state": "DIRECTLY_REPORTED",
     "validation_state": "UNVALIDATED",
     "transformation": "IDENTITY",
     "record_id": "epmc:41863498"
    }
   ],
   "opposition": {
    "considered": 4,
    "bound": 3
   },
   "synthesis": {
    "synthesis_id": "SYN-c6150506521fa4",
    "synthesis_outcome": "QUALITATIVE_ONLY",
    "direction_tally": {
     "UNCERTAIN": 2
    },
    "directional_disagreement": false,
    "heterogeneity": "not_assessed_quantitatively",
    "study_members": [
     "STU-9b0ebbc98359d4c3",
     "STU-ea5b5f1958d96737"
    ],
    "observations_pooled": 0
   }
  }
 ]
}